Mutations in activin receptor 1A (ACVR1A), which encodes the BMP type I receptor ALK2, cause fibrodysplasia ossificans progressiva (FOP), a rare dominant disorder leading to progressive ectopic bone formation in soft tissues with consequent severe impairment of body movements because of extraskeletal bone bridges that entrap the entire skeleton.7 ACVR1 mutations responsible for FOP cause dysregulation of SMAD-dependent downstream signaling and confer to the mutated receptor the ability to respond to a noncanonical ligand, activin A,8-10 triggering ectopic bone formation in tissue-resident, multipotent mesenchymal cells.11,12
This 108-bed residential substance abuse recovery center is centrally located on Lake Street in Richmond. Liberty Place works to restore opportunities to women by preparing them to lead sober, stable and productive lives. Services provided are free of charge to clients.
Liberty Place opened on June 30, 2008. As it is a 4 part program, the residents progress from Safe off the Streets where they live in a dormitory, into Motivational Track, where they start out living in another dorm and then move to a shared 2 person studio apartment, and then into Phase 1 which is the longest component of the program. Phase 1 and Phase 2 (transitional) clients remain in the 2 person studio apartments until they complete the program.
Safe Off the Street (SOS): Residents are screened by a telephone interview. Screenings determine appropriateness. Staff begins obtaining background information on residents. This includes resident history of addiction, family social history of their experience with alcohol and/or drugs, criminal justice system, etc. Residents are educated about the model that will help them live a sober life and are introduced to others that are living a life in recovery. They begin attending 12 Step meetings. SOS is a 16-bed dormitory.
MT2: Residents transition from the MT1 Dormitory into an apartment on the premises. This is called transitional housing. If a resident has income, they are required to pay 30% for their housing (including family sending spending money). However, most residents will not have any income at all. Residents are still trudging. Residents gain incentives for showing a willingness to invest in change.
Phase 2: Residents seek employment. Residents may become peer mentors for residents in the motivational or recovery phase of the program or may seek employment in the community. Residents work on maintaining sobriety, attend self-help meetings and participate in follow-up. As they progress, residents petition to move off-site and describe their plan of action for living as sober, productive members of society. Residents are still expected to participate in all program components including self-help and group meetings. Residents who complete this program and stay in compliance can always consider the program their home and can always return for support.
Although the panes were scored between the stamps, it was often necessary to separate them with scissors. All of the strip-type stamps have been imprinted with areas for license agents to fill in the hunter's conservation license number, as well as the month and day of issue. All of the strip-type stamps have been serial numbered in black. The serial number is made up of two components. The first component indicates the hunter's classification: "14" for residents; "15" for youths; and "22" for non-residents. The second component indicates of the sequential number of the stamp within the print run. For images of all stamps in this series from the classic period see 1969 - 1977 Montana Bird Stamps. 041b061a72